Functional dissection of complex trait variants at single-nucleotide resolution

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The approaches differ in where they draw the boundary. Namespaces use the same kernel but restrict visibility. Seccomp uses the same kernel but restricts the allowed syscall set. Projects like gVisor use a completely separate user-space kernel and make minimal host syscalls. MicroVMs provide a dedicated guest kernel and a hardware-enforced boundary. Finally, WebAssembly provides no kernel access at all, relying instead on explicit capability imports. Each step is a qualitatively different boundary, not just a stronger version of the same thing.

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